She is the world's greatest cat burglar, and an adversary/lover to Batman. But she's had enough of Gotham City and needs a break from the Dark Knight. What better escape than a European vacation? But it's not all fun and games, as there's business to take care of...

When in Rome chronicles Catwoman's mysterious trip to Italy and her dealings with the deadly Falcone crime family. While there, Catwoman must contend with some of Batman's deadliest villains, and a claw-tearing catfight with the lethal Cheetah! It's an incredible tale about Gotham's sexiest cat burglar.