When Julia Lambert, an art professor, settles into her idyllic Maine house for the summer, she plans to spend the time tending her fragile relationships with her father, a repressive neurosurgeon, and her gentle mother, who is descending into Alzheimer's. But a shattering revelation intrudes: Julia's son Jack has spiraled into heroin addiction.

In an attempt to save him, Julia marshals help from her looseknit clan: elderly parents; remarried ex-husband; removed sister; and combative eldest son. Ultimately, heroin courses through the characters' lives with an impersonal and devastating energy, sweeping the family into a world in which deceit, crime, and fear are part of daily life.