A former newspaper reporter and investigative journalist, Meredith O'Brien has written four books in a variety of genres.

A Boston area writer, she has two books slated for publication in 2025. Louie on the Rocks is a novel about the impact of Trump era political polarization on a family, and Uncomfortably Numb 2 is a guide for newly-diagnosed multiple sclerosis patients.

She's currently working on a work of creative nonfiction about the making of a Millennial Massachusetts minister.

In 2020, her medical memoir, "Uncomfortably Numb," chronicled the impact her diagnosis of multiple sclerosis has had on her life.

Her book -- "Mr. Clark's Big Band: A Year of Laughter, Tears and Jazz in a Middle School Band Room" -- won an Independent Book Publisher Award (Education category) and was a finalist for a Forewords INDIES Award (Education category). It follows a middle school jazz band from a small Massachusetts town that's led by a charismatic music director whose students are grieving the sudden loss of a band mate.

"Mortified: a novel about oversharing" follows a fictional mommy blogger who suffers the consequences after revealing too much personal information on the internet. It was a finalist for a Foreword Firsts Debut Novel contest.

Her first solo book was "A Suburban Mom: Notes from the Asylum," a collection of humor/parenting columns about raising her boy-girl twins and their younger brother.